A tropical fruit also known as the Malabar tamarind, is a popular weight-loss supplement. People say it blocks your body’s ability to make fat and it puts the brakes on your appetite. Loss of excess weight could help could help keep blood sugar and cholesterol levels in check, too. You’ll find it in bottles on the shelf at the store as well as mixed with other ingredients in diet products.
Health Benefits
- Clinically validated for its potential use in weight management
Action
It is reported that HCA reduces weight gain by inhibiting ATP citrate lyase, an enzyme which catalyzes the extra-mitochondrial cleavage of citrate to oxaloacetate and acetyl coenzyme A (acetyl-CoA), a building block of fatty acid synthesis.
By reducing the levels of acetyl-CoA and subsequently malonyl-CoA pool HCA limits the synthesis of fats and cholesterol.
The overall impact of this results in
- Suppression of food intake
- Decrease in de novo lipogenesis
- Increase in oxidation of fatty acids
- Reduction in glucose intake rates in tissues.
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